This study replicates and extends the findings of Budarick et al. 1, which demonstrated that a Spring Loaded knee brace can reduce knee joint loads to a level that would be achieved by losing 45 lb of bodyweight. In the present work, the authors used a validated biomechanical model to demonstrate that a tri-compartment offloader brace (TCO) can significantly reduce patellofemoral (PF) and tibiofemoral (TF) joint contact forces, as well as patellar tendon (PT), quadriceps tendon (QT), and posterior cruciate (PC) ligament forces during a deep knee bend from 30 to 100 degrees of joint flexion. To determine the potential of a TCO such as a Spring Loaded knee brace to offload knee joint forces, the offloading effects of three simulated TCO models (a squat, plateau, and general model) were compared to a non-braced condition. For all TCO models, knee joint loads were reduced by between 30-50% (Figure 1).